Isabella Norcliffe became friends with Anne in 1810. They remained friends and occasional lovers throughout the remainder of Anne’s life. Anne’s rejection of her as a life-partner was a bitter blow to Isabella, who remained single all her life. Anne disapproved of Isabella’’s drinking. As Isabella would come very much to regret, she introduced Anne to Mariana Belcombe, who would become lifelong lovers with Anne and the love of Anne’s life.